Chloroacetonitrile → HCID 54476035, 화합물

HRID 1580109노트

반응식

HRID 1580109 반응식
[CH3:1][N:2]([CH3:12])[C:3]1[CH:4]=[C:5]([OH:11])[C:6](=[CH:9][CH:10]=1)[CH:7]=[O:8].C(=O)([O-])[O-].[K+].[K+].Cl[CH2:20][C:21]#[N:22]>CC(C)=O>[CH:7]([C:6]1[CH:9]=[CH:10][C:3]([N:2]([CH3:12])[CH3:1])=[CH:4][C:5]=1[O:11][CH2:20][C:21]#[N:22])=[O:8]

참가 물질

5

반응물 3

HCID 7856ChloroacetonitrileHCID 11430Potassium CarbonateHCID 98153054-(dimethylamino)-2-hydroxybenzaldehyde

생성물 1

HCID 54476035HCID 54476035, 화합물

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

82 parts of 4-dimethylaminosalicylaldehyde is dissolved in 500 parts by volume of acetone, then 96 parts of potassium carbonate and 45 parts of chloroacetonitrile are added and the whole is boiled under reflux for 10 hours. After the solution has been filtered it is concentrated and the crystals deposited are recrystallized from benzene with the addition of animal charcoal. 36 parts of colorless crystals of 2-formyl-5-dimethylaminophenoxyacetonitrile is obtained with a melting point of 124° to 125°C.

후처리

  1. temperatureunder reflux for 10 hours
  2. filtrationAfter the solution has been filtered it
  3. concentrationis concentrated
  4. customthe crystals deposited are recrystallized from benzene with the addition of animal charcoal

출처 및 근거

ORD 기록
ord-9d1c6a998d93484390af7c4976fd287a
출처 데이터셋
uspto-grants-1976_01
특허 번호
US03932446

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