Potassium Carbonate → HCID 21565109, 화합물

HRID 1580110노트

반응식

HRID 1580110 반응식
[CH:1]([C:3]1[CH:12]=[CH:11][C:10]([N:13]([CH3:15])[CH3:14])=[CH:9][C:4]=1[O:5][CH2:6][C:7]#[N:8])=O.C(=O)([O-])[O-].[K+].[K+]>CN(C)C=O.O>[CH3:14][N:13]([CH3:15])[C:10]1[CH:11]=[CH:12][C:3]2[CH:1]=[C:6]([C:7]#[N:8])[O:5][C:4]=2[CH:9]=1

참가 물질

5

반응물 2

HCID 11430Potassium CarbonateHCID 54476035HCID 54476035, 화합물

생성물 1

HCID 21565109HCID 21565109, 화합물

시약·촉매·용매 2

HCID 962Water용매HCID 6228Dimethylformamide용매

실험 절차

15.3 parts of the nitrile is dissolved in 100 parts by volume of dimethylformamide and stirred with 10 parts of potassium carbonate for 15 hours at 70°C. The whole is then diluted with 1,000 parts of water, filtered by suction and the filter residue is dried. For further purification it is sublimed at 80°C and 1 mm and the sublimate is recrystallized from methylcyclohexane. The 6-dimethylaminobenzofuran-2-carbonitrile is obtained in the form of colorless crystals having a melting point of 70° to 71°C which dissolve in benzene with an intense blue-violet fluorescence.

후처리

  1. filtrationfiltered by suction
  2. customthe filter residue is dried
  3. customFor further purification it
  4. customis sublimed at 80°C
  5. custom1 mm and the sublimate is recrystallized from methylcyclohexane

출처 및 근거

ORD 기록
ord-0e158280b6ef485f855f0e0ca330ae56
출처 데이터셋
uspto-grants-1976_01
특허 번호
US03932446

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