Z-Asn-Leu-OMe → H-Asn-Leu-OMe
반응식
[NH:1](C(OCC1C=CC=CC=1)=O)[C@H:2]([C:7]([NH:9][C@H:10]([C:15]([O:17][CH3:18])=[O:16])[CH2:11][CH:12]([CH3:14])[CH3:13])=[O:8])[CH2:3][C:4](=[O:6])[NH2:5]>C(O)(C)(C)C.O.[Pd]>[NH2:1][C@H:2]([C:7]([NH:9][C@H:10]([C:15]([O:17][CH3:18])=[O:16])[CH2:11][CH:12]([CH3:14])[CH3:13])=[O:8])[CH2:3][C:4](=[O:6])[NH2:5]참가 물질
4
실험 절차
15.0 g of Z-Asn-Leu-OMe are dissolved in 400 ml of t-butanol-water (9:1) and are hydrogenated in the presence of 2 g of palladium on charcoal (10 % Pd). After completion of the hydrogenation the catalyst is filtered off and the filtrate evaporated at 40°C. The residue is directly used further.
후처리
- filtrationAfter completion of the hydrogenation the catalyst is filtered off
- customthe filtrate evaporated at 40°C
출처 및 근거
- ORD 기록
- ord-c78b611fae1a428fab8531515760856b
- 출처 데이터셋
- uspto-grants-1976_01
- 특허 번호
- US03934008
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