HCID 22723464, 화합물 → HCID 22723455, 화합물
반응식
C([O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[C:15]1[N:16]=[CH:17][O:18][CH:19]=1)C1C=CC=CC=1>ClCCl.[Pd]>[O:18]1[CH:19]=[C:15]([C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=2[OH:8])[N:16]=[CH:17]1참가 물질
4
실험 절차
To a solution of the oxazole from above (1.99 g, 7.92 mmol) in dichloromethane (20 ml) is added 10% palladium on carbon (1.99 g). The mixture is put under an atmosphere of hydrogen, stirred at room temperature over night, then filtered through Celite. The solvent is removed under reduced pressure to leave 2-(oxazol-4-yl)phenol (1.15 g, 90%), which is used for the next step without further purification.
후처리
- filtrationfiltered through Celite
- customThe solvent is removed under reduced pressure
출처 및 근거
- ORD 기록
- ord-28d2c149803b48fca9e0788fac35463b
- 출처 데이터셋
- uspto-grants-2004_05
- 특허 번호
- US06730792B2
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