Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,4-Dioxane hydrochloride → 2-Aminoindan-5-carboxylic acid morpholinamide hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,4-Dioxane hydrochloride | HCID 20443148 | — |
| 반응물 | 2-(Tert-butoxycarbonylamino)indan-5-carboxylic acid morpholinamide | HCID 131724366 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 2-Aminoindan-5-carboxylic acid morpholinamide hydrochloride | HCID 69849846 | — |
반응 단계
Using 2-(tert-butoxycarbonylamino)indan-5-carboxylic acid morpholinamide (1.0 g, 2.7 mmol), 4N hydrochloric acid-dioxane (12 ml) and acetic acid (36 ml), a similar procedure to Example 24 was carried out to obtain 2-aminoindan-5-carboxylic acid morpholinamide hydrochloride (750 mg, 2.7 mmol) having the following physical properties:
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06734180B1 |
| 출처 데이터셋 | uspto-grants-2004_05 |
| ORD ID | ord-d2bbbb28ee2842fabf798561437395ef |
| 출처 메모 | uspto-grants-2004_05 |