Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Anthranilic Acid → N-Methylanthranilic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Anthranilic Acid | HCID 227 | — |
| 반응물 | Formaldehyde | HCID 712 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Platinum oxide (PtO) | HCID 82844 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | N-Methylanthranilic acid | HCID 67069 | — |
반응 단계
A solution of 2-aminobenzoic acid (25 g) in ethanol (300 ml) reacted with an excess of paraformaldehyde and then reduced with hydrogen gas at 60 psi over platinum oxide (25 g) catalyst. After hydrogen uptake ceased, the mixture was filtered and the solvent removed on a rotary evaporator. The product was purified by chromatography on silica gel and the structure confirmed by nmr and infrared analysis.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04551279 |
| 출처 데이터셋 | uspto-grants-1985_11 |
| ORD ID | ord-ed246f2e1c7046a1a8e4929d902ad398 |
| 출처 메모 | uspto-grants-1985_11 |