2-Chloroethanol → Dithiaoctanediol

HRID 1583271

반응식

HRID 1583271 반응식
[CH2:1]([SH:4])[CH2:2][SH:3].[CH3:5][OH:6].[CH3:7][O-].[Na+].[CH2:10](Cl)[CH2:11][OH:12]>>[CH2:11]([OH:12])[CH2:10][S:3][CH2:2][CH2:1][S:4][CH2:7][CH2:5][OH:6]

참가 물질

5

반응물 4

HCID 342-ChloroethanolHCID 887MethanolHCID 109021,2-EthanedithiolHCID 10942334Sodium Methoxide

생성물 1

HCID 78904Dithiaoctanediol

실험 절차

In an ice bath, 25 g of dithioglycol was stirred and thereto, was added dropwise 1.1 equivalent of a methanol solution of sodium methoxide. Further, 44 g of ethylene chlorohydrin was added dropwise thereto. After the conclusion of the dropwise addition, the reaction mixture was allowed to stand for 10 hours at a room temperature. Then, sodium chloride deposited was removed by filtration, and the resulting filtrate was concentrated. The thus obtained white crystals were recrystallized from acetone. Melting Point 65° C., Yield 25 g.

후처리

  1. additionAfter the conclusion of the dropwise addition
  2. customThen, sodium chloride deposited was removed by filtration
  3. concentrationthe resulting filtrate was concentrated
  4. customThe thus obtained white crystals were recrystallized from acetone

출처 및 근거

ORD 기록
ord-2f4cb4a66e9242ea8816a9d8bece51dd
출처 데이터셋
uspto-grants-1985_11
특허 번호
US04551419

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