Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylformamide → 4-(2-Fluoroethoxy)isopropenylbenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 1-Chloro-2-fluoroethane | HCID 12983 | — |
| 반응물 | p-Isopropenylphenol | HCID 584247 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 4-(2-Fluoroethoxy)isopropenylbenzene | HCID 20259265 | 95.7% |
반응 단계
To 30 ml of dimethylformamide were added 7.0 g of 4-isopropenylphenol, 6.1 g of 1-fluoro-2-chloroethane and 8.7 g of potassium carbonate. With stirring, they were reacted at 120° C. for 4 hours. The reaction mixture was cooled to room temperature, and poured into water. The mixture was then extracted with toluene. The toluene layer was washed with water and dried over anhydrous sodium sulfate. Toluene was evaporated under reduced pressure to give 9.0 g of crude 4-(2-fluoroethoxy)isopropenylbenzene.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04552894 |
| 출처 데이터셋 | uspto-grants-1985_11 |
| ORD ID | ord-c8440b73d64141fe9a53354cfa7b5462 |
| 출처 메모 | uspto-grants-1985_11 |