Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dichromate ion → N-[N2-(1(S)-carboxy-3-phenylpropyl)-N6-carbamoylmethyl-L-lysyl]-L-proline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dichromate ion | HCID 24503 | — |
| 반응물 | 2-Hydroxyacetamide | HCID 69021 | — |
| 반응물 | Lisinopril | HCID 5362119 | — |
| 반응물 | 2-oxoacetamide | HCID 11708045 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 생성물 | N-[N2-(1(S)-carboxy-3-phenylpropyl)-N6-carbamoylmethyl-L-lysyl]-L-proline | HCID 86740515 | — |
반응 단계
In the manner described above in Example 1, N-[N2 (1(S)-carboxy-3-phenylpropyl)-L-lysyl]-L-proline and glyoxylic acid amide (which can be prepared by the oxidation of glycolamide with pyridinum dichromate) were hydrogenated in the presence of 10% Pd on carbon catalyst to yield N-[N2 -(1(S)-carboxy-3-phenylpropyl)-N6 -carbamoylmethyl-L-lysyl]-L-proline.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04555503 |
| 출처 데이터셋 | uspto-grants-1985_11 |
| ORD ID | ord-1358a9d2be3f4fc4960233821e9749b9 |
| 출처 메모 | uspto-grants-1985_11 |