4-Methylphthalic anhydride → 5-methyl-2-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-1H-isoindole-1,3(2H)-dione

HRID 15842

반응식

HRID 15842 반응식
[CH3:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][C:8]=2[N:12]2[CH2:17][CH2:16][N:15]([CH2:18][CH2:19][C:20]3[CH:21]=[C:22]([CH:24]=[CH:25][CH:26]=3)[NH2:23])[CH2:14][CH2:13]2)[N:3]=1.[CH3:27][C:28]1[CH:38]=[CH:37][C:31]2[C:32](=[O:36])[O:33][C:34](=O)[C:30]=2[CH:29]=1>>[CH3:27][C:28]1[CH:29]=[C:30]2[C:31](=[CH:37][CH:38]=1)[C:32](=[O:36])[N:23]([C:22]1[CH:24]=[CH:25][CH:26]=[C:20]([CH2:19][CH2:18][N:15]3[CH2:14][CH2:13][N:12]([C:8]4[CH:7]=[CH:6][CH:5]=[C:4]5[C:9]=4[CH:10]=[CH:11][C:2]([CH3:1])=[N:3]5)[CH2:17][CH2:16]3)[CH:21]=1)[C:34]2=[O:33]

참가 물질

3

반응물 2

HCID 880694-Methylphthalic anhydrideHCID 498521053-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline

생성물 1

HCID 574443275-methyl-2-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-1H-isoindole-1,3(2H)-dione

실험 절차

Prepared from 3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline (D6) and 5-methyl-2-benzofuran-1,3-dione according to Method I.

출처 및 근거

ORD 기록
ord-be96a93abf754fa9b79d7717f41e346c
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07732600B2

연결된 노트

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