Nitric Acid → 2,3-Dimethyl-5-nitroaniline

HRID 1585431노트

반응식

HRID 1585431 반응식
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[CH3:9].[N+:10]([O-])([OH:12])=[O:11]>S(=O)(=O)(O)O>[CH3:9][C:3]1[C:4]([CH3:8])=[CH:5][C:6]([N+:10]([O-:12])=[O:11])=[CH:7][C:2]=1[NH2:1]

참가 물질

4

반응물 2

HCID 944Nitric AcidHCID 68932,3-Dimethylaniline

생성물 1

HCID 8207862,3-Dimethyl-5-nitroaniline

시약·촉매·용매 1

HCID 1118Sulfuric Acid용매2회

반응 조건

온도
12 °C

실험 절차

363 g of 2,3-xylidine are run into 1.8 of pure sulphuric acid while the temperature is kept at 40° C. To this solution, cooled to 12° C., a sulphonitric mixture (132 ml of nitric acid (d=1.52) and 180 ml of pure sulphuric acid) is added dropwise over 1 hour, the temperature not exceeding 15° C. After 15 minutes the mixture is poured onto 6 kg of ice with stirring.

후처리

  1. customis kept at 40° C
  2. customexceeding 15° C

출처 및 근거

ORD 기록
ord-a1d0640c31e942a5ad204625165affa1
출처 데이터셋
uspto-grants-1999_08
특허 번호
US05938792

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