4H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride (1:1), (6aR)- → Apomorphine

HRID 1585445

반응식

HRID 1585445 반응식
[CH3:1][N:2]1[C@@H:11]2[CH2:12][C:13]3[CH:18]=[CH:17][C:16]([OH:19])=[C:15]([OH:20])[C:14]=3[C:9]3[C:10]2=[C:5]([CH:6]=[CH:7][CH:8]=3)[CH2:4][CH2:3]1.Cl.N[C@@H](CCC(N[C@H](C(NCC(O)=O)=O)CS)=O)C(O)=O>>[CH3:1][N:2]1[C@@H:11]2[CH2:12][C:13]3[CH:18]=[CH:17][C:16]([OH:19])=[C:15]([OH:20])[C:14]=3[C:9]3[C:10]2=[C:5]([CH:6]=[CH:7][CH:8]=3)[CH2:4][CH2:3]1

참가 물질

4

반응물 3

HCID 94104H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride (1:1), (6aR)-HCID 124886GlutathioneHCID 178504327HCID 178504327, 화합물

생성물 1

HCID 6005Apomorphine

실험 절차

An apomorphine transdermal patch formulation was prepared by adding 1 milliliter of a ethanolic solution of 20 mg/ml apomorphine HCl and 2.6 mg/ml glutathione to 2 g of polydimethylsiloxane 200 and mixing until the mixture congealed.

후처리

  1. additionmixing until the mixture

출처 및 근거

ORD 기록
ord-4ee8761c431847b4bc4142ac07a1b402
출처 데이터셋
uspto-grants-1999_08
특허 번호
US05939094

연결된 노트

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