Carbon Tetrachloride → Ethyl 3-bromo-6-methoxy-2-methylbenzoate

HRID 1586587

반응식

HRID 1586587 반응식
[CH3:1][C:2]1[C:7]([C:8]([O:10][CH2:11][CH3:12])=[O:9])=[C:6]([O:13][CH3:14])[CH:5]=[CH:4][CH:3]=1.[Br:15]Br.ClC(Cl)(Cl)Cl>O>[Br:15][C:3]1[CH:4]=[CH:5][C:6]([O:13][CH3:14])=[C:7]([C:2]=1[CH3:1])[C:8]([O:10][CH2:11][CH3:12])=[O:9]

참가 물질

5

반응물 3

HCID 5943Carbon TetrachlorideHCID 24408BromineHCID 5910602-Methoxy-6-methyl-benzoic acid ethyl ester

생성물 1

HCID 11022052Ethyl 3-bromo-6-methoxy-2-methylbenzoate

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A mixture of ethyl 6-methyl-2-methoxybenzoate (8.4 g, 43.2 mmol), bromine (6.9 g, 43.2 mmol) and tetrachloromethane (170 ml) is stirred at room temperature for 60 hours. The reaction mixture is poured into water and extracted with ethyl acetate. The organic phase is separated and concentrated. The crude product is obtained as a yellow oil, 10.3 g (87% y) and is used without further purification.

후처리

  1. extractionextracted with ethyl acetate
  2. customThe organic phase is separated
  3. concentrationconcentrated

출처 및 근거

ORD 기록
ord-764df8cc1a0c436faa7522f56ba7521e
출처 데이터셋
uspto-grants-1999_08
특허 번호
US05945567

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