2-Chloroethyl isocyanate → 1-(2-(Methoxy)-3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-imidazolidinone dihydrochloride
반응식
[CH3:1][O:2][C:3]1[C:9]([CH2:10][CH2:11][N:12]2[CH2:17][CH2:16][N:15]([C:18]3[CH:27]=[CH:26][CH:25]=[C:24]4[C:19]=3[CH:20]=[CH:21][C:22]([CH3:28])=[N:23]4)[CH2:14][CH2:13]2)=[CH:8][CH:7]=[CH:6][C:4]=1[NH2:5].[Cl:29][CH2:30][CH2:31][N:32]=[C:33]=[O:34]>>[ClH:29].[ClH:29].[CH3:1][O:2][C:3]1[C:9]([CH2:10][CH2:11][N:12]2[CH2:13][CH2:14][N:15]([C:18]3[CH:27]=[CH:26][CH:25]=[C:24]4[C:19]=3[CH:20]=[CH:21][C:22]([CH3:28])=[N:23]4)[CH2:16][CH2:17]2)=[CH:8][CH:7]=[CH:6][C:4]=1[N:5]1[CH2:30][CH2:31][NH:32][C:33]1=[O:34]참가 물질
3
실험 절차
The title compound was prepared in 38% yield according to the general procedure for the synthesis of cyclic ureas and carbamates (Method G) starting from 2-(methoxy)-3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline and 1-chloro-2-isocyanatoethane.
출처 및 근거
- ORD 기록
- ord-37b1bc585d1542849ddde7beed8e9c37
- 출처 데이터셋