Piperazine → 6-(2-Fluoro-4-iodophenylamino)-1,3-dimethyl-5-(piperazine-1-carbonyl)pyrimidine-2,4(1H,3H)-dione

반응식

[CH2:29]1[CH2:30][NH:31][CH2:32][CH2:33][NH:34]1.[F:1][c:2]1[c:3]([NH:9][c:10]2[c:11]([C:20]([O:22][c:21]3[cH:23][cH:24][cH:25][cH:26][cH:27]3)=[O:28])[c:12](=[O:19])[n:13]([CH3:18])[c:14](=[O:17])[n:15]2[CH3:16])[cH:4][cH:5][c:6]([I:8])[cH:7]1>>[F:1][c:2]1[c:3]([NH:9][c:10]2[c:11]([C:20](=[O:22])[N:31]3[CH2:30][CH2:29][NH:34][CH2:33][CH2:32]3)[c:12](=[O:19])[n:13]([CH3:18])[c:14](=[O:17])[n:15]2[CH3:16])[cH:4][cH:5][c:6]([I:8])[cH:7]1

참가 물질

반응물 2

HCID 4837Piperazine

HCID 59259226Phenyl 6-(2-fluoro-4-iodophenylamino)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

생성물 1

HCID 251090936-(2-Fluoro-4-iodophenylamino)-1,3-dimethyl-5-(piperazine-1-carbonyl)pyrimidine-2,4(1H,3H)-dione

출처 및 근거

ORD 기록: ord-d6abf006237f405d9dbd48a6e13c35d5
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

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