Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 3-methyl-2-[(2-phenoxyacetyl)amino]benzoic Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Phenoxyacetyl chloride | HCID 69703 | — |
| 반응물 | 2-Amino-3-methylbenzoic acid | HCID 78101 | — |
| 용매 | Sodium Hydroxide | HCID 14798 | — |
| 생성물 | 3-methyl-2-[(2-phenoxyacetyl)amino]benzoic Acid | HCID 3560808 | 47% |
반응 단계
3-Methylanthranilic acid 5 g (33 mmol) was dissolved in 10% aqueous sodium hydroxide solution 27 ml and to this solution, phenoxyacetyl chloride 6.2 g (36 mmol) was added dropwise at 0° C. The resulting solution was stirred at room temperature for 1 hour and acidified with 10% hydrochloric acid solution. Deposited crystals were collected by filtration, washed with water and recrystallized from ethanol to obtain 3-methyl-N-(phenoxyacetyl)anthranilic acid (melting point: 174° to 176° C.) 4.4 g (yield: 47%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05217961 |
| 출처 데이터셋 | uspto-grants-1993_06 |
| ORD ID | ord-ca19d20234ad4e699ea96efbe2252535 |
| 출처 메모 | uspto-grants-1993_06 |