Water → 1-(2-n-Propylphenyliminomethyl)-nitroiminoimidazolidine

HRID 1587737노트

반응식

HRID 1587737 반응식
FC(F)(F)C(O)=O.[CH2:8]([C:11]1[CH:17]=[CH:16][CH:15]=[CH:14][C:12]=1[NH2:13])[CH2:9][CH3:10].CN1CCN(C)C1=O.O.C(O[CH:30](OCC)[N:31]1[CH2:35][CH2:34][NH:33][C:32]1=[N:36][N+:37]([O-:39])=[O:38])C>>[CH2:8]([C:11]1[CH:17]=[CH:16][CH:15]=[CH:14][C:12]=1[N:13]=[CH:30][N:31]1[CH2:35][CH2:34][NH:33][C:32]1=[N:36][N+:37]([O-:39])=[O:38])[CH2:9][CH3:10]

참가 물질

6

반응물 5

HCID 962WaterHCID 6422Trifluoroacetic acidHCID 66611,3-Dimethyl-2-imidazolidinoneHCID 157592-PropylanilineHCID 1364034191-Diethoxymethyl-2-nitroiminoimidazolidine

생성물 1

HCID 1363314791-(2-n-Propylphenyliminomethyl)-nitroiminoimidazolidine수율 31.7%

실험 절차

0.05 g of trifluoroacetic acid was dropped in a mixture of 5.0 g of 1-diethoxymethyl-2-nitroiminoimidazolidine, 2.48 g of o-n-propylaniline and 2 ml of 1,3-dimethyl-2-imidazolidinone at 90° C., followed by agitation at the same temperature for 45 minutes. The reaction mixture was poured into water, extracted with ethyl acetate, washed with water, dried and evaporated. Ether was added to the resultant oily residue and the resultant crystals were separated by filtration and dried to give 1.6 g of 1-(2-n-propylphenyliminomethyl)-2-nitroiminoimidazolidine.

후처리

  1. extractionextracted with ethyl acetate
  2. washwashed with water
  3. customdried
  4. customevaporated
  5. additionEther was added to the resultant oily residue
  6. customthe resultant crystals were separated by filtration
  7. customdried

출처 및 근거

ORD 기록
ord-c27990dcc2e14504beb5d4846ea6d595
출처 데이터셋
uspto-grants-1993_06
특허 번호
US05219868

반응 노트

불러오는 중…