Water → 1-(4-Isopropylphenyliminomethyl)-2-nitroiminoimidazolidine

HRID 1587738노트

반응식

HRID 1587738 반응식
S(=O)(=O)(O)O.[CH:6]([C:9]1[CH:15]=[CH:14][C:12]([NH2:13])=[CH:11][CH:10]=1)([CH3:8])[CH3:7].CN1CCN(C)C1=O.O.C(O[CH:28](OCC)[N:29]1[CH2:33][CH2:32][NH:31][C:30]1=[N:34][N+:35]([O-:37])=[O:36])C>>[CH:6]([C:9]1[CH:15]=[CH:14][C:12]([N:13]=[CH:28][N:29]2[CH2:33][CH2:32][NH:31][C:30]2=[N:34][N+:35]([O-:37])=[O:36])=[CH:11][CH:10]=1)([CH3:8])[CH3:7]

참가 물질

6

반응물 5

HCID 962WaterHCID 1118Sulfuric AcidHCID 66611,3-Dimethyl-2-imidazolidinoneHCID 74644-IsopropylanilineHCID 1364034191-Diethoxymethyl-2-nitroiminoimidazolidine

생성물 1

HCID 1363314851-(4-Isopropylphenyliminomethyl)-2-nitroiminoimidazolidine수율 41.6%

실험 절차

0.05 g of concentrated sulfuric acid was dropped in a mixture of 5.0 g of 1-diethoxymethyl-2-nitroiminoimidazolidine, 2.48 g of p-isopropylaniline and 2 ml of 1,3-dimethyl-2-imidazolidinone at 110° C., followed by agitation at the same temperature for 1 hour. The reaction mixture was poured into water, extracted with ethyl acetate, washed with water, dried and evaporated. Ether was added to the resultant oily residue and the resultant crystals were separated by filtration and dried to obtain 2.1 g of 1-(4-isopropylphenyliminomethyl)-2-nitroiminoimidazolidine.

후처리

  1. extractionextracted with ethyl acetate
  2. washwashed with water
  3. customdried
  4. customevaporated
  5. additionEther was added to the resultant oily residue
  6. customthe resultant crystals were separated by filtration
  7. customdried

출처 및 근거

ORD 기록
ord-90ef4de4147945ed80cb39b27f60a45d
출처 데이터셋
uspto-grants-1993_06
특허 번호
US05219868

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