Triethylamine → HCID 19757146, 화합물

HRID 1588083노트

반응식

HRID 1588083 반응식
[F:1][As-:2]([F:7])([F:6])([F:5])([F:4])[F:3].[OH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[S+:15]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[OH:29])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[OH:22].C(N([CH2:35][CH3:36])CC)C.[O:37]([CH:44]([O:46][C:47]1[CH:52]=[CH:51][CH:50]=[CH:49][CH:48]=1)Cl)[C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1>O1CCCC1>[F:1][As-:2]([F:7])([F:6])([F:5])([F:4])[F:3].[O:37]([CH:44]([O:46][C:36]1[CH:35]=[CH:52][CH:47]=[CH:48][CH:49]=1)[O:29][C:24]1[CH:25]=[CH:26][CH:27]=[CH:28][C:23]=1[S+:15]([C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=1[O:8][CH:44]([O:46][C:47]1[CH:48]=[CH:49][CH:50]=[CH:51][CH:52]=1)[O:37][C:38]1[CH:39]=[CH:40][CH:41]=[CH:42][CH:43]=1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[O:22][CH:44]([O:46][C:47]1[CH:52]=[CH:51][CH:50]=[CH:49][CH:48]=1)[O:37][C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1)[C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1

참가 물질

5

반응물 3

HCID 8471TriethylamineHCID 133499351,1'-[(Chloromethylene)bis(oxy)]dibenzeneHCID 19757136HCID 19757136, 화합물

생성물 1

HCID 19757146HCID 19757146, 화합물

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

20 parts of tris(hydroxyphenyl)sulfonium hexafluoroarsenate are dissolved in 100 parts of tetrahydrofuran. 12.2 parts of triethylamine are added, followed dropwise by the gradual addition of 30 parts of diphenoxychloromethane, and the mixture is stirred at room temperature for 24 hours. The mixture is then washed with water, and the organic solution is dried over a molecular sieve and evaporated in a rotary evaporator. Chromatographic purification leaves 14.8 parts of the expected product. IR and NMR agree with the expected structure.

후처리

  1. washThe mixture is then washed with water
  2. customthe organic solution is dried over a molecular sieve
  3. customevaporated in a rotary evaporator
  4. customChromatographic purification

출처 및 근거

ORD 기록
ord-3b04850d5672413585af27cd638ea366
출처 데이터셋
uspto-grants-1993_06
특허 번호
US05220037

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