2,3-Dibromopropionamide → 4-(3,5-Dimethoxyphenyl)-1-(phenylmethyl)-2-piperazinecarboxamide

반응식

[CH3:1][O:2][C:3]1[CH:4]=[C:5]([NH:11][CH2:12][CH2:13][NH:14][CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH:6]=[C:7]([O:9][CH3:10])[CH:8]=1.Br[CH:23]([CH2:27]Br)[C:24]([NH2:26])=[O:25]>>[CH3:10][O:9][C:7]1[CH:6]=[C:5]([N:11]2[CH2:12][CH2:13][N:14]([CH2:15][C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH:23]([C:24]([NH2:26])=[O:25])[CH2:27]2)[CH:4]=[C:3]([O:2][CH3:1])[CH:8]=1

참가 물질

반응물 2

HCID 857982,3-Dibromopropionamide

HCID 19755034N-(3,5-dimethoxyphenyl)-N'-(phenylmethyl)-1,2-ethanediamine

생성물 1

HCID 149987644-(3,5-Dimethoxyphenyl)-1-(phenylmethyl)-2-piperazinecarboxamide

실험 절차

In a manner similar to Preparation 1, react N-(3,5-dimethoxyphenyl)-N'-(phenylmethyl)-1,2-ethanediamine with 2,3-dibromopropanamide to obtain the title compound.

후처리

customIn a manner similar to Preparation 1

출처 및 근거

ORD 기록: ord-bcae608e9f52430eb6e8ce1272efe58c
출처 데이터셋: uspto-grants-1993_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05223623

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