4-(3,5-Dimethoxyphenyl)-1-(phenylmethyl)-2-piperazinemethanamine → N-[[4-(3,5-Dimethoxyphenyl)-1-(phenylmethyl)piperazin-2-yl]methyl]-4-[(ethylsulfonyl)amino]benzenesulfonamide

HRID 1589005노트

반응식

HRID 1589005 반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([N:11]2[CH2:16][CH2:15][N:14]([CH2:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[CH:13]([CH2:24][NH2:25])[CH2:12]2)[CH:6]=[C:7]([O:9][CH3:10])[CH:8]=1.[CH2:26]([S:28]([NH:31][C:32]1[CH:37]=[CH:36][C:35]([S:38](Cl)(=[O:40])=[O:39])=[CH:34][CH:33]=1)(=[O:30])=[O:29])[CH3:27]>>[CH3:10][O:9][C:7]1[CH:6]=[C:5]([N:11]2[CH2:16][CH2:15][N:14]([CH2:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[CH:13]([CH2:24][NH:25][S:38]([C:35]3[CH:34]=[CH:33][C:32]([NH:31][S:28]([CH2:26][CH3:27])(=[O:30])=[O:29])=[CH:37][CH:36]=3)(=[O:40])=[O:39])[CH2:12]2)[CH:4]=[C:3]([O:2][CH3:1])[CH:8]=1

참가 물질

3

반응물 2

HCID 149987744-(3,5-Dimethoxyphenyl)-1-(phenylmethyl)-2-piperazinemethanamineHCID 149987924-[(Ethylsulfonyl)amino]benzenesulfonyl chloride

생성물 1

HCID 14998793N-[[4-(3,5-Dimethoxyphenyl)-1-(phenylmethyl)piperazin-2-yl]methyl]-4-[(ethylsulfonyl)amino]benzenesulfonamide

실험 절차

In a manner similar to Preparation 3, react 4-(3,5-dimethoxyphenyl)-1-(phenylmethyl)-2-piperazinemethanamine with 4-[(ethylsulfonyl)amino]benzenesulfonyl chloride to obtain the title compound.

후처리

  1. customIn a manner similar to Preparation 3

출처 및 근거

ORD 기록
ord-efad923bbaad4ac59c9d58c3c6555266
출처 데이터셋
uspto-grants-1993_06
특허 번호
US05223623

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