3-Methyl-1-naphthyl acetate → 1-Naphthol, 3-methyl-

HRID 1589730노트

반응식

HRID 1589730 반응식
C([O:4][C:5]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH:8]=[C:7]([CH3:15])[CH:6]=1)(=O)C>[OH-].[K+]>[CH3:15][C:7]1[CH:6]=[C:5]([OH:4])[C:14]2[C:9]([CH:8]=1)=[CH:10][CH:11]=[CH:12][CH:13]=2

참가 물질

3

반응물 1

HCID 137648093-Methyl-1-naphthyl acetate

생성물 1

HCID 261351-Naphthol, 3-methyl-수율 27.7%

시약·촉매·용매 1

HCID 14797Potassium Hydroxide용매

실험 절차

Crude 1-acetoxy-3-methylnaphthalene (84 g, 0.42 mole) was boiled with 10% ethanolic potassium hydroxide (300 cm3) for 3 hours. Ethanol was distilled off and the residue dissolved in water and extracted with toluene to remove neutral products. The aqueous alkaline solution was carefully acidified with dilute hydrochloric acid and the liberated 3-methyl-l-naphthol extracted with ether. The ether extract was washed with water, dried and filtered. Ether solvent was removed leaving 3-methyl-l-naphthol (18.4 g) as clear colorless crystals.

후처리

  1. distillationEthanol was distilled off
  2. dissolutionthe residue dissolved in water
  3. extractionextracted with toluene
  4. customto remove neutral products
  5. extractionthe liberated 3-methyl-l-naphthol extracted with ether
  6. extractionThe ether extract
  7. washwas washed with water
  8. customdried
  9. filtrationfiltered
  10. customEther solvent was removed

출처 및 근거

ORD 기록
ord-12990e0e8b8d420b9995ac40ed251615
출처 데이터셋
uspto-grants-1993_04
특허 번호
US05200116

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