Thionyl Chloride → HCID 178447883, 화합물

HRID 1589738노트

반응식

HRID 1589738 반응식
O=S(Cl)[Cl:3].[CH2:5]([C@H:8]1[CH2:13][CH2:12][C@H:11]([C:14]2[CH:22]=[CH:21][C:17]([C:18](O)=[O:19])=[CH:16][CH:15]=2)[CH2:10][CH2:9]1)[CH2:6][CH3:7]>>[CH2:5]([C@H:8]1[CH2:13][CH2:12][C@H:11]([C:14]2[CH:22]=[CH:21][C:17]([C:18]([Cl:3])=[O:19])=[CH:16][CH:15]=2)[CH2:10][CH2:9]1)[CH2:6][CH3:7]

참가 물질

3

반응물 2

HCID 24386Thionyl ChlorideHCID 178447888HCID 178447888, 화합물

생성물 1

HCID 178447883HCID 178447883, 화합물수율 96.2%

실험 절차

In 75 cm3 (1.0 mol) of SOCl2, 128 g (0.52 mol) of 4-(trans-4'-propylcyclohexyl) benzoic acid was refluxed for 3 hours. The excess SOCl2 was distilled off under a reduced pressure and the residue was distilled under reduced pressure (158° C./3.0 mmHg) to yield 133 g (0.50 mol) of 4-(trans-4'-propylcyclohexyl) benzoic acid chloride.

후처리

  1. distillationThe excess SOCl2 was distilled off under a reduced pressure
  2. distillationthe residue was distilled under reduced pressure (158° C./3.0 mmHg)

출처 및 근거

ORD 기록
ord-8eaca0e6aa924d44805999afc6b806fe
출처 데이터셋
uspto-grants-1993_04
특허 번호
US05200110

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