(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal → Methyl 2-chloro-3-hydroxy-3-(p-methoxyphenyl)propionate

참여 물질

반응 단계

In a test tube with an outer diameter of 15 mm, 0.25 g of a baker's yeast (Saccharomyces cerevisiae, manufactured by Oriental Kobo Kogyo K K ) was suspended in 3 ml of a McIlvaine buffer containing 0.54 g of glucose dissolved therein, and then 6 μl of dimethylformamide containing 6 mg of methyl 2-chloro-3-oxo-3-(p-methoxyphenyl)propionate was charged, followed by shaking reaction at 30° C. for 24 hours. When the reaction mixture was extracted with 2 ml of ethyl acetate and the amount of methyl 2-chloro-3-hydroxy-3-(p-methoxyphenyl)propionate formed was quantitated, it was found that 0.6 mg of the product was formed.

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