Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → 2-Cyano-5-(dimethylamino)-N,N-dimethylpenta-2,4-dienamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | Piperidine | HCID 8082 | — |
| 반응물 | 3-(Dimethylamino)-2-propenal | HCID 79125 | — |
| 반응물 | 2-Cyano-N,N-dimethylacetamide | HCID 251143 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 2-Cyano-5-(dimethylamino)-N,N-dimethylpenta-2,4-dienamide | HCID 54570707 | 70.4% |
반응 단계
3-Dimethylaminoacrolein (25 g, 0.25 mol) and cyanoacetic acid N,N-dimethylamide (28 g, 0.25 mol) were dissolved in toluene (250 ml) and piperidine (1 ml) and acetic acid (2.5 ml) were then added. The solution was heated under reflux in a water separator until no more water was formed (about 2 hours). The solution was then filtered and reduced to about 100 ml. On cooling, crystals formed which were filtered off under suction and dried to give 34 g 1-cyano-1- dimethylaminocarbonyl-4-dimethylamino-1,3-butadiene as yellow-brown crystals, m.pt. 149°-150° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05206372 |
| 출처 데이터셋 | uspto-grants-1993_04 |
| ORD ID | ord-2d74e6310d284c6db3fc4c34764ee7ea |
| 출처 메모 | uspto-grants-1993_04 |