돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1591466생성일: 2026년 10월 27일

(S)-3-Amino-4,5-dihydro-1H-benzo[b]azepin-2(3H)-one → 3-Benzyloxycarbonylamino-3-methyl-N-[2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepin-3(S)-yl]-butanamide

https://huagongshe.com/reaction/1591466

반응식

참여 물질

역할이름HCID투입량
반응물(S)-3-Amino-4,5-dihydro-1H-benzo[b]azepin-2(3H)-oneHCID 10241317—
반응물3-(((Benzyloxy)carbonyl)amino)-3-methylbutanoic acidHCID 14551007—
생성물3-Benzyloxycarbonylamino-3-methyl-N-[2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepin-3(S)-yl]-butanamideHCID 18651462—

반응 단계

Prepared from 3(S)-amino-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one (Example 1, Step B) and 3-benzyloxycarbonylamino-3-methylbutanoic acid (Example 1, Step E) by the procedure described in Example 1, Step F. FAB-MS: calculated for C23H27N3O4 409; found 410 (M+H,100%). [a]D =- 160° (c=1,CHCl3).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05206235
출처 데이터셋uspto-grants-1993_04
ORD IDord-a83d346f1224478788849bb68f8a6592
출처 메모uspto-grants-1993_04