Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
tert-Butyl 4-oxopiperidine-1-carboxylate → 4-[(3,5-Dimethyl-pyridin-2-ylmethyl)-amino]-piperidine-1-carboxylic acid tert-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | tert-Butyl 4-oxopiperidine-1-carboxylate | HCID 735900 | — |
| 반응물 | Sodium triacetoxyborohydride | HCID 5049666 | — |
| 반응물 | (3,5-Dimethylpyridin-2-yl)methanamine | HCID 18507412 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 4-[(3,5-Dimethyl-pyridin-2-ylmethyl)-amino]-piperidine-1-carboxylic acid tert-butyl ester | HCID 67271627 | — |
반응 단계
Using General Procedure B, reaction of N-Boc-4-piperidone, C-(3,5-dimethylpyridin-2-yl)-methylamine and NaBH(OAc)3 in CH2Cl2 gave 4-[(3,5-dimethyl-pyridin-2-ylmethyl)-amino]-piperidine-1-carboxylic acid tert-butyl ester.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07291631B2 |
| 출처 데이터셋 | uspto-grants-2007_11 |
| ORD ID | ord-e472c2c7e0f641ee812ebebee861bd4e |
| 출처 메모 | uspto-grants-2007_11 |