3,6-Dichloropyridazine → tert-Butyl 4-(((6-chloropyridazin-3-yl)(methyl)amino)methyl)piperidine-1-carboxylate

반응식

[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH:11]([CH2:14][NH:15][CH3:16])[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[Cl:17][C:18]1[N:19]=[N:20][C:21](Cl)=[CH:22][CH:23]=1>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH:11]([CH2:14][N:15]([C:21]2[N:20]=[N:19][C:18]([Cl:17])=[CH:23][CH:22]=2)[CH3:16])[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

참가 물질

반응물 2

HCID 673313,6-Dichloropyridazine

HCID 21934652tert-Butyl 4-((methylamino)methyl)piperidine-1-carboxylate

생성물 1

HCID 71647826tert-Butyl 4-(((6-chloropyridazin-3-yl)(methyl)amino)methyl)piperidine-1-carboxylate

실험 절차

From 1-t-butoxycarbonyl-4-[(methylamino)methyl]piperidine and 3,6-dichloropyridazine.

출처 및 근거

ORD 기록: ord-de663c7f2c554af5aa20f6e1fa1e72c7
출처 데이터셋: uspto-grants-2007_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07294627B2

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