3-(Dimethylamino)-1-(4-fluorophenyl)-2-(pyridin-4-yl)prop-2-en-1-one → HCID 178505592, 화합물
반응식
C[N:2](C)[CH:3]=[C:4]([C:14]1[CH:19]=[CH:18][N:17]=[C:16]([F:20])[CH:15]=1)[C:5]([C:7]1[CH:12]=[CH:11][C:10]([F:13])=[CH:9][CH:8]=1)=O.C[N:23](C)C=C(C1C=CN=CC=1)C(C1C=CC(F)=CC=1)=O>>[F:13][C:10]1[CH:11]=[CH:12][C:7]([C:5]2[C:4]([C:14]3[CH:19]=[CH:18][N:17]=[C:16]([F:20])[CH:15]=3)=[CH:3][NH:2][N:23]=2)=[CH:8][CH:9]=1참가 물질
3
실험 절차
The reaction was carried out in the same manner as in Example 1-2) except for using 4.17 g (14.5 mmol) of 3-dimethylamino-1-(4-fluorophenyl)-2-(2-fluoropyridin-4-yl)-2-propen-1-one obtained in Example 17-1) in place of 3-dimethylamino-1-(4-fluorophenyl)-2-(pyridin-4-yl)-2-propen-1-one to obtain 3.28 g of the title compound as a white powder. (Yield: 88%)
출처 및 근거
- ORD 기록
- ord-7e254161aa1842e98e8b5be7a9b5aa12
- 출처 데이터셋
- uspto-grants-2007_11