Acetyl chloride → N-(4-(5-Cyano-1-methyl-1H-pyrrol-2-yl)phenyl)acetamide

HRID 1593558노트

반응식

HRID 1593558 반응식
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:12]([CH3:13])[C:11]([C:14]#[N:15])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[C:16](Cl)(=[O:18])[CH3:17]>>[C:14]([C:11]1[N:12]([CH3:13])[C:8]([C:5]2[CH:6]=[CH:7][C:2]([NH:1][C:16](=[O:18])[CH3:17])=[CH:3][CH:4]=2)=[CH:9][CH:10]=1)#[N:15]

참가 물질

3

반응물 2

HCID 6367Acetyl chlorideHCID 160504305-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrile

생성물 1

HCID 16037464N-(4-(5-Cyano-1-methyl-1H-pyrrol-2-yl)phenyl)acetamide

실험 절차

The title compound was prepared according to the general procedure for acylation of 5-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrile using acetyl chloride (39 μL, 0.55 mmol) to provide N-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)phenyl]acetamide (0.018 g).

후처리

  1. customThe title compound was prepared

출처 및 근거

ORD 기록
ord-f4f2e6673a9f4affbfcdfa293119a0d1
출처 데이터셋
uspto-grants-2007_11
특허 번호
US07297713B2

반응 노트

불러오는 중…