Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Bromine → 5-Bromo-2-hydroxypyridine-3-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Bromine | HCID 24408 | — |
| 반응물 | 3-Cyano-2-pyridone | HCID 577543 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 5-Bromo-2-hydroxypyridine-3-carbonitrile | HCID 7204870 | — |
반응 단계
Bromine (29 ml, 560 mmol) was added to a stirred solution of 2-oxo-1,2-dihydro-pyridine-3-carbonitrile (34 g, 280 mmol) in acetic acid (180 ml) at room temperature. After 14 hours the reaction mixture was concentrated in vacuo and the resulting oil was trituated with ethanol to afford the title compound as a solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07297792B2 |
| 출처 데이터셋 | uspto-grants-2007_11 |
| ORD ID | ord-bad87c6cf601468b882f553d00f8474a |
| 출처 메모 | uspto-grants-2007_11 |