Hydrazinium chloride → HCID 178468624, 화합물

HRID 1593679노트

반응식

HRID 1593679 반응식
[F:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[CH:4][C:3]=1[C:9](=O)[CH2:10][C:11](O)([C:17]([O:19][CH2:20][CH3:21])=[O:18])[C:12](OCC)=[O:13].Cl.[NH2:25][NH2:26]>C(O)C>[F:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[CH:4][C:3]=1[C:9]1[N:26]=[N:25][C:12]([OH:13])=[C:11]([C:17]([O:19][CH2:20][CH3:21])=[O:18])[CH:10]=1

참가 물질

4

반응물 2

HCID 115031Hydrazinium chlorideHCID 21948264Diethyl 2-[2-(2,3-difluorophenyl)-2-oxoethyl]-2-hydroxymalonate

생성물 1

HCID 178468624HCID 178468624, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

Diethyl 2-[2-(2,3-difluorophenyl)-2-oxoethyl]-2-hydroxymalonate (18.50 g, 56.1 mmol) and hydrazine monohydrochloride (4.03 g, 58.8 mmol) were stirred at reflux in ethanol (300 mL) for 96 h, and then evaporated to dryness to afford the title compound as a solid.

후처리

  1. customevaporated to dryness

출처 및 근거

ORD 기록
ord-31c496e3f457487ba0bc418613b8e1c0
출처 데이터셋
uspto-grants-2007_11
특허 번호
US07297792B2

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