Piperidine → HCID 21074077, 화합물

반응식

Cl[CH2:2][CH2:3][C:4]([NH:6][C:7]1[CH:20]=[CH:19][C:18]2[NH:17][C:16]3[C:11](=[CH:12][C:13]([NH:21][C:22](=[O:26])[CH2:23][CH2:24]Cl)=[CH:14][CH:15]=3)[C:10](=[O:27])[C:9]=2[CH:8]=1)=[O:5].[NH:28]1[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]1>>[N:28]1([CH2:2][CH2:3][C:4]([NH:6][C:7]2[CH:20]=[CH:19][C:18]3[NH:17][C:16]4[C:11](=[CH:12][C:13]([NH:21][C:22](=[O:26])[CH2:23][CH2:24][N:17]5[CH2:18][CH2:9][CH2:10][CH2:11][CH2:16]5)=[CH:14][CH:15]=4)[C:10](=[O:27])[C:9]=3[CH:8]=2)=[O:5])[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]1

참가 물질

반응물 2

HCID 8082Piperidine

HCID 21074075HCID 21074075, 화합물

생성물 1

HCID 21074077HCID 21074077, 화합물

실험 절차

Chloroamide 13 (400 mg, 1.0 mmol) was treated with piperidine (3 mL) according to the general aminolysis procedure to give the desired product BR-ACO-17 (300 mg, 61%) as a dark yellow solid.

출처 및 근거

ORD 기록: ord-1b44846d3876497eb639dad4089f4c4d
출처 데이터셋: uspto-grants-2007_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07300930B2

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