Ammonia → HCID 136343466, 화합물

HRID 1594068노트

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HRID 1594068 반응식
C([O:3][C:4]([C:6]1[N:7]=[C:8]([C:11]2[NH:12][CH:13]=[CH:14][N:15]=2)[S:9][CH:10]=1)=O)C.[NH3:16]>CO>[NH:15]1[CH:14]=[CH:13][N:12]=[C:11]1[C:8]1[S:9][CH:10]=[C:6]([C:4]([NH2:16])=[O:3])[N:7]=1

참가 물질

4

반응물 2

HCID 222AmmoniaHCID 136343490HCID 136343490, 화합물

생성물 1

HCID 136343466HCID 136343466, 화합물

시약·촉매·용매 1

HCID 887Methanol용매

반응 조건

온도
60 °C

실험 절차

A solution of 2-(1H-Imidazole-2-yl)-thiazole-4-carboxylic acid ethyl ester (190 mg) in 5 mL of MeOH is saturated with NH3 gas, and heated at 60° C. in a sealed tube overnight. After cooled, the reaction mixture is transferred to a round bottle flask and evaporated in vacuo to a solid. LRMS calcd 194, found 195 (MH+).

후처리

  1. temperatureAfter cooled
  2. customthe reaction mixture is transferred to a round bottle flask
  3. customevaporated in vacuo to a solid

출처 및 근거

ORD 기록
ord-a8697457e2ca475a9be6a38e48f61c92
출처 데이터셋
uspto-grants-2007_11
특허 번호
US07300945B2

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