Hexafluoroacetone → CH2=C(CF3)CF2Ocf(CF3)2

HRID 1594458노트

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HRID 1594458 반응식
[CH2:1]=[C:2]([C:7]([O:10]S(F)(=O)=O)([F:9])[F:8])[C:3]([F:6])([F:5])[F:4].[C:15](O[K])([C:21]([F:24])([F:23])[F:22])([C:17]([F:20])([F:19])[F:18])[F:16].[F-].[K+].FC(F)(F)C(C(F)(F)F)=O>O.COCCOCCOC>[CH2:1]=[C:2]([C:7]([O:10][C:15]([C:21]([F:24])([F:23])[F:22])([C:17]([F:20])([F:19])[F:18])[F:16])([F:9])[F:8])[C:3]([F:6])([F:5])[F:4]

참가 물질

7

반응물 4

HCID 12695HexafluoroacetoneHCID 522689Potassium FluorideHCID 87741755CH2=C(CF3)CF2Oso2FHCID 178506340HCID 178506340, 화합물

생성물 1

HCID 131726622CH2=C(CF3)CF2Ocf(CF3)2수율 75%

시약·촉매·용매 2

HCID 962Water용매HCID 8150Diglyme용매

실험 절차

CH2═C(CF3)CF2OSO2F (10 g, 0.041 mole) is added at 20° C. to (CF3)2CFOK, prepared from freshly dried potassium fluoride (KF) (2.4 g, 0.041 mole), hexafluoroacetone (HFA) (9.3 g, 0.056 mole) and dry diglyme (10 ml). The reaction mixture is agitated for 2 hours and then poured into water, the organic layer separating. The organic layer is washed with dilute hydrochloric acid, then sodium bicarbonate solution, then water, after which it is dried over magnesium sulfate (MgSO4). Distillation of the reaction mixture gives CH2═C(CF3)CF2OCF(CF3)2 (10.2 g, 75% yield, b.pt. 87-88° C.).

후처리

  1. customthe organic layer separating
  2. washThe organic layer is washed with dilute hydrochloric acid
  3. dry with materialsodium bicarbonate solution, then water, after which it is dried over magnesium sulfate (MgSO4)
  4. distillationDistillation of the reaction mixture

출처 및 근거

ORD 기록
ord-1ffe82ee73284e6f94c8aa82185afd74
출처 데이터셋
uspto-grants-2007_11
특허 번호
US07301059B2

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