Triethylamine → CH2=C(CF3)CF2OC6F5

HRID 1594464노트

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HRID 1594464 반응식
[F:1][C:2]1[C:7]([OH:8])=[C:6]([F:9])[C:5]([F:10])=[C:4]([F:11])[C:3]=1[F:12].C(N(CC)CC)C.[CH2:20]=[C:21]([C:26](OS(F)(=O)=O)([F:28])[F:27])[C:22]([F:25])([F:24])[F:23]>C(OCC)C>[CH2:20]=[C:21]([C:26]([O:8][C:7]1[C:6]([F:9])=[C:5]([F:10])[C:4]([F:11])=[C:3]([F:12])[C:2]=1[F:1])([F:28])[F:27])[C:22]([F:25])([F:24])[F:23]

참가 물질

5

반응물 3

HCID 8471TriethylamineHCID 13041PentafluorophenolHCID 87741755CH2=C(CF3)CF2Oso2F

생성물 1

HCID 85887664CH2=C(CF3)CF2OC6F5수율 74.7%

시약·촉매·용매 1

HCID 3283Diethyl Ether용매2회

반응 조건

온도
20 °C

실험 절차

Pentafluorophenol (7.5 g, 0.040 mole) and triethylamine (4.5 g, 0.044 mole) in dry ethyl ether (7 ml) are added gradually to CH2═C(CF3)CF2OSO2F (11 g, 0.045 mole) in ethyl ether (14 ml) at 20° C. The reaction mixture is agitated at 20° C. for 30 minutes and washed in turn with water, dilute aqueous HCl, water, sodium bicarbonate solution, and water and the resulting ether solution is dried over MgSO4. Distillation of the dried mixture gives CH2═C(CF3)CF2OC6F5 (9.8 g, 73% yield, b.pt. 86-88° C. at 20 mm Hg).

후처리

  1. washwashed in turn with water, dilute aqueous HCl, water, sodium bicarbonate solution, and water
  2. dry with materialthe resulting ether solution is dried over MgSO4
  3. distillationDistillation of the dried mixture

출처 및 근거

ORD 기록
ord-46cd501b4cfb4f8a851d715a3559ef81
출처 데이터셋
uspto-grants-2007_11
특허 번호
US07301059B2

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