4-Toluenesulfonyl chloride → (RS)-1-(Toluene-4-sulfonyl)-2-m-tolyl-pyrrolidine

반응식

[C:1]1([CH3:12])[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]2[CH2:11][CH2:10][CH2:9][NH:8]2)[CH:2]=1.[C:13]1([CH3:23])[CH:18]=[CH:17][C:16]([S:19](Cl)(=[O:21])=[O:20])=[CH:15][CH:14]=1>>[C:13]1([CH3:23])[CH:18]=[CH:17][C:16]([S:19]([N:8]2[CH2:9][CH2:10][CH2:11][CH:7]2[C:3]2[CH:2]=[C:1]([CH3:12])[CH:6]=[CH:5][CH:4]=2)(=[O:21])=[O:20])=[CH:15][CH:14]=1

참가 물질

반응물 2

HCID 73974-Toluenesulfonyl chloride

HCID 35440982-(3-Methylphenyl)pyrrolidine

생성물 1

HCID 11290026(RS)-1-(Toluene-4-sulfonyl)-2-m-tolyl-pyrrolidine

실험 절차

The title compound, off-white solid, m.p. 79° C. and MS: m/e=315 (M+) was prepared in accordance with the general method of example 1e from (RS)-2-m-tolyl-pyrrolidine and toluene-4-sulfonyl chloride.

출처 및 근거

ORD 기록: ord-df6ff040b81445c4bb0ef6795d616176
출처 데이터셋: uspto-grants-2001_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06284785B1

반응 노트

불러오는 중…