4-Chlorobenzenesulfonyl chloride → HCID 40432134, 화합물

HRID 1594757노트

반응식

HRID 1594757 반응식
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C@@H:8]2[CH2:12][CH2:11][CH2:10][NH:9]2)=[CH:4][CH:3]=1.[Cl:13][C:14]1[CH:19]=[CH:18][C:17]([S:20](Cl)(=[O:22])=[O:21])=[CH:16][CH:15]=1>>[Cl:13][C:14]1[CH:19]=[CH:18][C:17]([S:20]([N:9]2[CH2:10][CH2:11][CH2:12][C@H:8]2[C:5]2[CH:4]=[CH:3][C:2]([F:1])=[CH:7][CH:6]=2)(=[O:22])=[O:21])=[CH:16][CH:15]=1

참가 물질

3

반응물 2

HCID 73984-Chlorobenzenesulfonyl chlorideHCID 7022776(S)-2-(4-Fluorophenyl)pyrrolidine

생성물 1

HCID 40432134HCID 40432134, 화합물

실험 절차

The title compound, white solid, m.p. 120° C. and MS: m/e=339 (Me) was prepared in accordance with the general method of example 1e from (S)-2-(4-fluoro-phenyl)-pyrrolidine and 4-chloro-benzenesulfonyl chloride.

출처 및 근거

ORD 기록
ord-8cc6c83e62384b01904a8808741213e6
출처 데이터셋
uspto-grants-2001_09
특허 번호
US06284785B1

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