3-Pyridinemethanamine → HCID 178470197, 화합물

참여 물질

반응 단계

Ethyl 2-hydroxyimino-3-(4-methylphenyl)-3-oxopropionate (10.0 g) and 3-aminomethylpyridine (5.3 ml) were reacted and treated in the same manner as in Starting Material Synthetic Example 1 to give ethyl 5-(4-methylphenyl)-2-(3-pyridyl)imidazole-4-carboxylate (4.0 g). 0.5 g therefrom was dissolved in ethyl alcohol (10 ml), and the mixture was reacted and treated in the same manner as in Starting Material Synthetic Example 2 to give 5-(4-methylphenyl)-2-(3-pyridyl)-imidazole-4-carboxylic acid (0.39 g), melting point 140-142° C.

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