3-Pyridinemethanamine → HCID 178470197, 화합물

HRID 1595331

반응식

HRID 1595331 반응식
O[N:2]=[C:3]([C:9]([C:11]1[CH:16]=[CH:15][C:14]([CH3:17])=[CH:13][CH:12]=1)=O)[C:4]([O:6][CH2:7][CH3:8])=[O:5].[NH2:18][CH2:19][C:20]1[CH:21]=[N:22][CH:23]=[CH:24][CH:25]=1>>[CH3:17][C:14]1[CH:15]=[CH:16][C:11]([C:9]2[NH:18][C:19]([C:20]3[CH:21]=[N:22][CH:23]=[CH:24][CH:25]=3)=[N:2][C:3]=2[C:4]([O:6][CH2:7][CH3:8])=[O:5])=[CH:12][CH:13]=1

참가 물질

3

반응물 2

HCID 310183-PyridinemethanamineHCID 178472891HCID 178472891, 화합물

생성물 1

HCID 178470197HCID 178470197, 화합물

실험 절차

Ethyl 2-hydroxyimino-3-(4-methylphenyl)-3-oxopropionate (10.0 g) and 3-aminomethylpyridine (5.3 ml) were reacted and treated in the same manner as in Starting Material Synthetic Example 1 to give ethyl 5-(4-methylphenyl)-2-(3-pyridyl)imidazole-4-carboxylate (4.0 g). 0.5 g therefrom was dissolved in ethyl alcohol (10 ml), and the mixture was reacted and treated in the same manner as in Starting Material Synthetic Example 2 to give 5-(4-methylphenyl)-2-(3-pyridyl)-imidazole-4-carboxylic acid (0.39 g), melting point 140-142° C.

후처리

  1. additiontreated in the same manner as

출처 및 근거

ORD 기록
ord-3148abd9eb214a1c8dd97a9865ee4985
출처 데이터셋
uspto-grants-2001_09
특허 번호
US06288061B1

연결된 노트

불러오는 중…