(2-Nitrophenyl)methanamine → HCID 178470184, 화합물

참여 물질

반응 단계

Ethyl 2-hydroxyimino-3-(4-methylphenyl)-3-oxopropionate (12.8 g) and 2-nitrobenzylamine (8.6 g) were reacted and treated in the same manner as in Starting Material Synthetic Example 1 to give ethyl 5-(4-methylphenyl)-2-(2-nitrophenyl)imidazole-4-carboxylate(3.5g). 3.0 g therefrom was dissolved in ethyl alcohol (100 ml) and 1 M sodium hydroxide solution (20 ml) was added. The mixture was reacted and treated in the same manner as in Starting Material Synthetic Example 2 to give 5-(4-methylphenyl)-2-(2-nitrophenyl)imidazole-4-carboxyic acid (2.4 g), melting point 144° C. (decomposition).

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