[4-(Aminomethyl)phenyl]methanol → HCID 178450798, 화합물

HRID 1595380노트

반응식

HRID 1595380 반응식
[OH:1][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][NH2:10])=[CH:5][CH:4]=1.[Cl:11][C:12]1[CH:17]=[CH:16][C:15]([C:18](=O)[C:19](=[N:27]O)[C:20]([O:22][C:23]([CH3:26])([CH3:25])[CH3:24])=[O:21])=[CH:14][CH:13]=1>N1C=CC=CC=1>[Cl:11][C:12]1[CH:17]=[CH:16][C:15]([C:18]2[NH:10][C:9]([C:6]3[CH:7]=[CH:8][C:3]([CH2:2][OH:1])=[CH:4][CH:5]=3)=[N:27][C:19]=2[C:20]([O:22][C:23]([CH3:26])([CH3:25])[CH3:24])=[O:21])=[CH:14][CH:13]=1

참가 물질

4

반응물 2

HCID 6496943[4-(Aminomethyl)phenyl]methanolHCID 178451307HCID 178451307, 화합물

생성물 1

HCID 178450798HCID 178450798, 화합물

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

4-(Hydroxymethyl)phenylmethylamine and tert-butyl 3-(4-chlorophenyl)-2-hydroxyimino-3-oxopropionate are dissolved in pyridine, and the mixture is treated in the same manner as in Starting Material Synthetic Example 170 to give the objective tert-butyl 5-(4-chlorophenyl)-2-(4-hydroxymethylphenyl)imidazole-4-carboxylate.

후처리

  1. additionthe mixture is treated in the same manner as

출처 및 근거

ORD 기록
ord-c10877665546470898d9ab45806218dc
출처 데이터셋
uspto-grants-2001_09
특허 번호
US06288061B1

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