4,5-Dihydro-2-thiazolamine → HCID 178489031, 화합물

HRID 1595422노트

반응식

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[NH:13][C:12]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([N+:20]([O-:22])=[O:21])[CH:15]=3)=[N:11][C:10]=2[C:23](O)=[O:24])=[CH:5][CH:4]=1.S(Cl)(Cl)=O.[NH2:30][C:31]1[S:32][CH2:33][CH2:34][N:35]=1>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[NH:13][C:12]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([N+:20]([O-:22])=[O:21])[CH:15]=3)=[N:11][C:10]=2[C:23]([NH:30][C:31]2[S:32][CH2:33][CH2:34][N:35]=2)=[O:24])=[CH:5][CH:4]=1

참가 물질

반응물 3

HCID 156894,5-Dihydro-2-thiazolamine

HCID 24386Thionyl Chloride

HCID 178489035HCID 178489035, 화합물

생성물 1

HCID 178489031HCID 178489031, 화합물

실험 절차

5-(4-Methoxyphenyl)-2-(3-nitrophenyl )imidazole-4-carboxylic acid, 1 M hydrochloric acid—ether solution, thionyl chloride and 2-aminothiazoline are reacted and treated in the same manner as in Example 1 to give 5-(4-methoxyphenyl)-2-(3-nitrophenyl)-N-(2-thiazolinyl)imidazole-4-carboxamide.

후처리

additiontreated in the same manner as in Example 1

출처 및 근거

ORD 기록: ord-465b6976f27e47a8985d311bb5aad990
출처 데이터셋: uspto-grants-2001_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06288061B1

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