Bis(2-chloroethyl)ethylamine → 4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-ethyl-piperidine-4-carboxylic acid ethyl ester

참여 물질

역할	이름	HCID	투입량
반응물	Bis(2-chloroethyl)ethylamine	HCID 10848	—
반응물	HCID 11121795	HCID 11121795	—
생성물	4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-ethyl-piperidine-4-carboxylic acid ethyl ester	HCID 11762171	—

반응 단계

4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-ethyl-piperidine-4-carboxylic acid ethyl ester was prepared according to the general method outlined in example 83 starting from [4-(4-chloro-phenoxy)-benzenesulfonyl]-acetic acid ethyl ester (4 g, 11.3 mmol) and ethyl-bis-(2-chloro-ethyl)-amine (2.32 g, 16.9 mmol). Yield 3.36 g (66%); brown oil; MS: 452.0 (M+H)+

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US06288086B1
출처 데이터셋	uspto-grants-2001_09
ORD ID	ord-38e57f5b266a4937b34145bdea9c680f
출처 메모	uspto-grants-2001_09