Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenylpropanolamine → (1S,2R)-2-amino-1-phenylpropan-1-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenylpropanolamine | HCID 10297 | — |
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | (1S,2R)-2-amino-1-phenylpropan-1-ol | HCID 26934 | — |
반응 단계
As shown in the scheme above, (1R, 2S)-(−)- norephedrine is reacted with an optionally substituted benzaldehyde by refluxing in ethanol, and reducing the product of that reaction with sodium borohydride at ambient temperature to produce the desired norephedrine derivative compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06288233B1 |
| 출처 데이터셋 | uspto-grants-2001_09 |
| ORD ID | ord-b28c151d057f4f0bbcfc10c69ab8201e |
| 출처 메모 | uspto-grants-2001_09 |