Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Bromonaphthalene-2-carbaldehyde → (1-Bromonaphthalen-2-yl)methanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Bromonaphthalene-2-carbaldehyde | HCID 76909 | — |
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | (1-Bromonaphthalen-2-yl)methanol | HCID 13113200 | 92.3% |
반응 단계
A solution of 1-bromo-2-naphthaldehyde (2.12 g, 8.91 mmol) in MeOH under N2 at 0° C. was treated with NaBH4 (0.51 g, 13.4 mmol), stirred for 15 minutes, quenched with acetone, and concentrated. Purification on silica gel with 5% ethyl acetate/CH2Cl2 provided 1.95 g (92%) of the desired compound as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06288261B1 |
| 출처 데이터셋 | uspto-grants-2001_09 |
| ORD ID | ord-6e3aac090eda42cfb50f990f50991962 |
| 출처 메모 | uspto-grants-2001_09 |