(+-)-Homocysteine → Captopril

HRID 1596152

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HRID 1596152 반응식
N[C@@H](CCC(N[C@H:11]([C:14]([NH:16][CH2:17][C:18]([OH:20])=[O:19])=[O:15])[CH2:12][SH:13])=O)C(O)=O.N[C@H:22]([C:25](O)=O)[CH2:23]S.N[CH:29](C(O)=O)CCS.CN(C1C=CC2N=C3C(=CC(C=C3)=[N+](C)C)SC=2C=1)C.C(N[C@H](C(O)=O)CS)(=O)C>>[CH3:29][C@@H:11]([C:14]([N:16]1[C@H:17]([C:18]([OH:20])=[O:19])[CH2:25][CH2:22][CH2:23]1)=[O:15])[CH2:12][SH:13]

참가 물질

6

실험 절차

Glutathione, L-cysteine, DL-homocysteine, D-penicillin, hemoglobin (bovine), methylene blue and Medium 199 sets were purchased from Sigma Chemical Co., St. Louis, Mo. N-acetylcysteine was obtained from Aldrich Chemical Co., Milwaukee, Wis. Captopril was kindly provided by Dr. Victor Dzau. Sodium nitrite, histamine and methacholine were purchased from Fisher Scientific, Fairlawn, N.J. Leukotriene D4 was purchased from Anaquest, BOC Inc., Madison, Wis. Antibiotic/antimycotic mixture (10,000 U/ml penicillin G sodium, 10,000 mg/ml, streptomycin sulfate, 25 mg/ml amphotericin B) was purchased from Gibco laboratories, Grand Island, N.Y. Radioimmunoassay kits for the determination of cyclic GMP were purchased from New England Nuclear, Boston, Mass.

출처 및 근거

ORD 기록
ord-23115e2efe9343e6bff157cbea07d9a4
출처 데이터셋
uspto-grants-2001_09
특허 번호
US06291424B1

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