Bromine → 2-Bromo-1-(4-bromo-2-methoxyphenyl)ethanone
반응식
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:10])[CH3:9])=[C:4]([O:11][CH3:12])[CH:3]=1.[Br:13]Br>O1CCOCC1>[Br:13][CH2:9][C:8]([C:5]1[CH:6]=[CH:7][C:2]([Br:1])=[CH:3][C:4]=1[O:11][CH3:12])=[O:10]참가 물질
4
실험 절차
To a stirred solution of 1-(4-bromo-2-methoxyphenyl)-1-ethanone (31.5 g, 138 mmol) in dioxane (32 ml) was added a solution of bromine (21.8 g, 136 mmol) in dioxane (123 ml), and the mixture was stirred for 3 hours. Then the volatile was evaporated in vacuo. The residue was recystallized with hexane-dichloromethane to give title compound (32.1 g, 76% yield).
후처리
- customThen the volatile was evaporated in vacuo
출처 및 근거
- ORD 기록
- ord-21eb4ba799954e0da3d856214a5d89e0
- 출처 데이터셋
- uspto-grants-2001_09
- 특허 번호
- US06294558B1
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