Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Chloro-6,7,8-trimethoxyquinazoline → 4-(6-Chloro-2,3-dihydro-indol-1-yl)-6,7,8-trimethoxy-quinazoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Chloro-6,7,8-trimethoxyquinazoline | HCID 100686 | — |
| 반응물 | 6-Chloro-2,3-dihydro-1h-indole | HCID 258567 | — |
| 용매 | Isopropanol | HCID 3776 | — |
| 생성물 | 4-(6-Chloro-2,3-dihydro-indol-1-yl)-6,7,8-trimethoxy-quinazoline | HCID 18932909 | 20% |
반응 단계
Utilizing a procedure analogous to that described in Example 1, this product was prepared in 20% yield from 6-chloro-indoline (1.1 eq.) and 4-chloro-6,7,8-trimethoxy-quinazoline (1.0 eq) in i-PrOH. (M.P. 139°-143° C.; GC/MS: 371 (M+); anal. RP18-HPLC RT: 4.70 min.).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05736534 |
| 출처 데이터셋 | uspto-grants-1998_04 |
| ORD ID | ord-c66a990478814585a3ac201247fd0751 |
| 출처 메모 | uspto-grants-1998_04 |