4-Iodo-o-toluidine → 2-Chloro-3-(2-fluoro-4-iodophenylamino)-isonicotinic acid

반응식

[CH3:19][c:20]1[cH:21][c:22]([I:23])[cH:24][cH:25][c:26]1[NH2:27].[F:1][c:2]1[c:3]([NH:9][c:10]2[c:11]([C:12](=[O:13])[OH:14])[cH:15][cH:16][n:17][cH:18]2)[cH:4][cH:5][c:6]([I:8])[cH:7]1.[F:28][c:29]1[c:30]([Cl:38])[c:31]([C:35]([OH:36])=[O:37])[cH:32][cH:33][n:34]1>>[F:1][c:2]1[c:3]([NH:9][c:10]2[c:11]([C:12](=[O:13])[OH:14])[cH:15][cH:16][n:17][c:18]2[Cl:38])[cH:4][cH:5][c:6]([I:8])[cH:7]1

참가 물질

반응물 3

HCID 832214-Iodo-o-toluidine

HCID 121754283-Chloro-2-fluoropyridine-4-carboxylic acid

HCID 590267913-((2-Fluoro-4-iodophenyl)amino)isonicotinic acid

생성물 1

HCID 576496342-Chloro-3-(2-fluoro-4-iodophenylamino)-isonicotinic acid

출처 및 근거

ORD 기록: ord-6305181cbaca479fa7ed1324a4e78f5a
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

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